Early chronic kidney disease usually has no symptoms. These symptoms tend to occur as the disease advances:

• Appetite loss

• Feeling generally unwell or fatigued

• Itching and dry skin

• Nausea

• Weight loss

But because they are similar to symptoms that can occur with other ailments, they are often overlooked. This is a cause for concern, as the earlier kidney disease is diagnosed and treated the easier it is to limit loss of kidney function.

The following symptoms may occur as kidney disease worsens:

• Abnormally dark or light skin

• Bone pain

• Drowsiness and confusion

• Difficulty thinking

• Numbness in the hands, feet or other areas

• Muscle twitching

• Easy bruising, bleeding, or blood in the stool

• Excessive thirst

• Frequent hiccups

• Low level of sexual interest and impotence

• Menstrual periods stop (amenorrhea)

• Shortness of breath

• Sleep problems, such as insomnia, restless leg syndrome, and obstructive sleep apnea

• Swelling of the feet and hands (edema)

• Vomiting, typically in the morning