A natural ingredient found in milk may offer protection against obesity, even for those who eat a high-fat diet, according to a new study of mice that researchers said has significant implications for people.
Scientists who conducted the study, published in the journal Cell Metabolism, said the milk ingredient -- known as “nicotinamide riboside” – is comparable to a new kind of vitamin.
Lead researcher Johan Auwerx, of École Polytechnique Fédérale de Lausanne, said his scientific team identified the fat-fighting ingredient while searching for alternative ways to boost the activity of a well-known gene – called “SIRT1” -- linked to health and longevity. Past studies have found the gene responds to the disease-fighting antioxidant resveratrol, found in red wine and other foods.
Auwerx's team found mice given high doses of nicotinamide riboside -- along with high-fat meals -- burned more fat, were less likely to be obese and had greater muscle endurance. Auwerx said the team will now study the effects of the compound – incorporated into a metabolism-boosting dietary supplement -- in people.
He suggested the milk ingredient may offer benefits similar to those attributed to resveratrol.
“It's possible that many small effects of ingredients found in our diets could add up to slimmer waistlines — perhaps longer lives, too,” he said.