Scientists at Queen's University Belfast have made what they are describing as a breakthrough in the fight against resistant hospital superbugs.
The gels break down the thick jelly-like coating, known as biofilms, that cover bacteria making them highly resistant to drugs.
"When bacteria attach to surfaces, including medical implants such as hip replacements and catheters, they produce a jelly-like substance called the biofilm,” noted Garry Laverty, M.D., from the School of Pharmacy at Queen's University.
"This protective layer is almost impossible for current antibiotics to penetrate through. Therefore bacteria deep within this protective layer are resistant as they remain unexposed to the therapy. They grow and thrive on surfaces to cause infections that are very difficult to treat. The only option is often to remove the medical implant leading to further pain and discomfort for the patient. Our gels would prevent this."
The innovative gels are made of natural proteins, called peptides, that rapidly kill bacteria, the scientists reported in the journal Biomacromolecules.
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