Tags: snake | venom | varespladib | pill

New Pill Could Save Lives After Venomous Snake Bite

rattlesnake ready to bite
(Dreamstime)

By    |   Wednesday, 27 December 2023 03:23 PM EST

The World Health Organization estimates that 138,000 people are killed by venomous snakes annually, and most of them die before they reach emergency medical care. But a new drug is being tested that could save lives.

According to the Los Angeles Times, the medication, Varespladib, blocks phospholipase-A2, a highly toxic protein that is present in 98% of all snake venoms. The protein is responsible for life-threatening tissue destruction, catastrophic bleeding, paralysis, and respiratory failure.

Currently the drug is in clinical trials conducted by Ophirex Inc., a public benefit corporation that was founded by Dr. Matthew Lewin, an internationally recognized expert in the practice of emergency medicine and wilderness medicine.

The U.S. Food and Drug Administration granted Varespladib a “fast track” designation to expedite the development and review of its safety and effectiveness last year. The Department of Defense has also invested $24 million into the effort, says the Times.

Experts say that the drug would be of great value where snake bites are more common and could be used to buy time before being able to get the hospital. But getting any new drug from the laboratory to the market is an expensive and intricate process that may take years to accomplish.

Ophirex is now completing a Phase II clinical trial in the United States and India to determine the tolerability and potential side effects of multi-dose regimens of the drug in 100 suspected or confirmed snakebite victims.

A federal analysis of the results is expected next year to determine whether Ophirex has created a successful treatment for snakebites that will have both military and global opportunities. The price for the proposed pill has not been established, but the company says they want to make the drug accessible around the world, and to make that a reality, they are exploring ways to reduce manufacturing costs.

Lynn C. Allison

Lynn C. Allison, a Newsmax health reporter, is an award-winning medical journalist and author of more than 30 self-help books.

© 2026 NewsmaxHealth. All rights reserved.


Health-News
The World Health Organization estimates that 138,000 people are killed by venomous snakes annually, and most of them die before they reach emergency medical care. But a new drug is being tested that could save lives. According to the Los Angeles Times, the medication,...
snake, venom, varespladib, pill
306
2023-23-27
Wednesday, 27 December 2023 03:23 PM
Newsmax Media, Inc.

Sign up for Newsmax’s Daily Newsletter

Receive breaking news and original analysis - sent right to your inbox.

(Optional for Local News)
Privacy: We never share your email address.
Join the Newsmax Community
Read and Post Comments
Please review Community Guidelines before posting a comment.
 
Find Your Condition
Get Newsmax Text Alerts
TOP

The information presented on this website is not intended as specific medical advice and is not a substitute for professional medical treatment or diagnosis. Read Newsmax Terms and Conditions of Service.

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

NEWSMAX.COM
© Newsmax Media, Inc.
All Rights Reserved
NEWSMAX.COM
© Newsmax Media, Inc.
All Rights Reserved