Tags: Health Topics | Saliva | Alzheimer’s | Amyloid Protein

Saliva Test Predicts Alzheimer's

Saliva Test Predicts Alzheimer's

(Dreamstime)

By    |   Monday, 21 November 2016 12:23 PM

A new saliva test could revolutionize the diagnosing — and predicting — of Alzheimer's disease, and could pave the way for new preventive measures and care.


Aurin Biotech developed the test, following a controlled study, which is based on measuring the concentration of amyloid beta protein in saliva. Amyloid protein is the substance present in the brains of Alzheimer's patients and is believed to be what causes the inflammation that kills off brain neurons. The company announced the development on its website, aurinbiotech.com, and published its findings in the Journal of Alzheimer's disease.

Researchers at Aurin analyzed amyloid protein levels in 25 people used as controls. They ranged in age from 15 to 92 years, and had amyloid protein levels in their saliva averaging 23.34 picograms per ml. Six Alzheimer’s disease cases had values more than twice as high, ranging from 41.58 to 75.20 picograms per ml.

One 51 year old, who was cognitively normal but destined to develop Alzheimer disease, had a value of 60.90, slightly higher than the average for Alzheimer disease cases. Two other cases, aged 52 and 60, who were also cognitively normal but were known from their family histories to be at high risk for Alzheimer’s disease, had values of 47.96 and 59.57 picograms per ml.

The study appears to show that nature tightly controls amyloid protein production in every organ of the body and keeps it at the same production rate throughout life. In normal individuals, this rate is almost exactly the same regardless of sex or age. However, for those destined to develop Alzheimer’s disease the rate varies, but is two to three times higher.

“We believe that a teaspoon of saliva can predict an individual’s chances of getting Alzheimer’s disease, and that once you know your chances you can take early preventive measures,” Dr. Pat McGeer, president and CEO of Aurin Biotech, said. “Knowing is the key, and that’s what this simple test is all about.” He added: If individuals know they are destined to develop Alzheimer disease, they can initiate preventive measures. These include taking over-the-counter non-steroidal anti-inflammatory drugs such as ibuprofen, drinking coffee, and sticking to a Mediterranean diet."

 

 


 

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A new saliva test could revolutionize the diagnosing — and predicting — of Alzheimer's disease, and could pave the way for new preventive measures and care.
Saliva, Alzheimer’s, Amyloid Protein
357
2016-23-21
Monday, 21 November 2016 12:23 PM
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