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Tags: coronavirus | nasal spray

Nasal Spray Blocks COVID-19 Infection in Ferrets

coronavirus
(Dreamstime)

By    |   Friday, 06 November 2020 10:51 AM EST

An inexpensive nasal spray prevented ferrets from contracting COVID-19, according to new study by scientists at Columbia University.

The pre-print study released Thursday found that the nontoxic and temperature-stable spray prevented the coronavirus from attaching to cells. The key ingredient in the novel nasal spray is a lipopeptide, a cholesterol-like particle that’s made of the same chain of amino acids as the virus’ spike protein.

According to The New York Times, the virus must unzip itself to release the spike protein that attaches to cells. As it does this, the lipopeptide charges in and latches on to one of the virus’ amino acids so it cannot affix itself to the cell.

“It is like you are zipping a zipper but you put another zipper inside, so the two sides cannot meet,” explained Matteo Porotto, Ph.D., associate professor of viral molecular pathogenesis at Columbia University and one of the study authors.

The researchers used two groups of ferrets for their experiment because they catch viruses nasally like humans. Both groups were injected with SARS-CoV-2, the virus responsible for COVID-19. One group of ferrets received a placebo while the second got the protective nasal spray. After 24 hours, even though the ferrets were living together in the same cages, the ones that got the placebo developed the disease, while sprayed ferrets did not.

“Virus replication was completely blocked,” said the authors, according to the Times, who said the protective effect lasted 24 hours.

According to The Business Standard, the research has been underway for months. The next step is obtaining funding for human clinical trials to see if a daily spritz of the nasal spray can ward off infection.

“If it works this well in humans, you could sleep in the same bed with someone infected or be with your infected kids and still be safe,” said Dr. Anne Moscano, professor of pediatrics and microbiology at Columbia University, and co-author of the study.

© 2024 NewsmaxHealth. All rights reserved.


Headline
An inexpensive nasal spray prevented ferrets from contracting COVID-19, according to new study by scientists at Columbia University. The pre-print study released Thursday found that the nontoxic and temperature-stable spray...
coronavirus, nasal spray
323
2020-51-06
Friday, 06 November 2020 10:51 AM
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