When Topher Grace played the character Venom in "Spider-Man 3," he said, "I had four hours of prosthetic makeup every morning."

Rhys Ifans, who played the Lizard in "The Amazing Spider-Man" and "Spider-Man: No Way Home," spent up to eight hours in the makeup chair to become the scaly supervillain.

That’s their job, and they accept the discomfort and risks that come with it. But for young kids and preteens who love face painting, use a touch of lip gloss, or sprinkle on some glitter, the risks are not worth taking.

That's the conclusion of a new survey published in the International Journal of Environmental Research and Public Health. Researchers found that about 54% of kids under age 12 use children's makeup and body products at least monthly, 12% use them daily, and about 20% use such products for eight hours or more at a time.

And that's a problem because, the researchers say, many children's makeup and body products contain toxins such as asbestos, phthalates, formaldehyde, and forever-chemicals called PFAs, as well as heavy metals.

These substances can disrupt hormones (make male frogs female), trigger chronic inflammation, and increase the risk for diseases such as cancer. 

For holiday or party fun, you can make face paints from vegetable dyes or use masks and props. But discourage use of makeup products.

While children are more susceptible to the effects of toxins than adults, you might also think about what it is that you use that may contain these chemicals.