Dr. Mike Roizen
Dr. Mike Roizen is chief medical officer at the Cleveland Clinic Wellness Institute, an award-winning author, and has been the doctor to eight Nobel Prize winners and more than 100 Fortune 500 CEOs.

Dr. Mike Roizen

Tags: heart failure | diabetes | calcium | dr. roizen
OPINION

New Treatment for Heart Failure

Michael Roizen, M.D. By Wednesday, 11 May 2022 12:15 PM EDT Current | Bio | Archive

The "Star Trek" universe knows about transporter inhibitors. For instance, Lieutenant Commander Data used one while on a Federation mission scout ship to prevent himself from being beamed away by a USS Enterprise-E shuttlecraft.

Sodium-Glucose Cotransporter-2 Inhibitors may provide similarly effective protection from medical woes for people with heart failure.

Known as SGLT2 inhibitors, this Type 2 diabetes medication lowers blood sugar by causing the kidneys to remove sugar from the body through the urine.

But according to a new study in Annals of Internal Medicine, it is also hugely beneficial for people with heart failure, regardless of whether or not they have diabetes.

Researchers analyzed eight randomized, controlled trials that included more than 15,000 participants, and found that after one year of treatment, SGLT2 inhibitors were associated with a 32% lower risk for hospitalization due to heart failure and a 26% reduction after two years.

In addition, the medication reduced the risk of cardiovascular death by 14%.

It seems to work by reducing the sodium content in heart cells, which reduces a calcium overload that can cause arrhythmias.

But — and there is always a but — the medication does have side effects. The researchers highlighted the risk of genital infections, and the Food and Drug Administration says that it also has been associated with kidney problems, leg and foot amputations, decreased bone mineral density, and urinary tract infections.

If you have heart failure, ask your doctor about the benefits and risks of SGLT2 inhibitors for you. And check out the Cleveland Clinic's "Living with Heart Failure" information at www.clevelandclinic.org.

© King Features Syndicate


DrRoizen
The new treatment seems to work by reducing the sodium content in heart cells, which reduces a calcium overload that can cause arrhythmias.
heart failure, diabetes, calcium, dr. roizen
259
2022-15-11
Wednesday, 11 May 2022 12:15 PM
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