Dr. Gary Small, M.D.

2 Weeks To a Younger Brain
Misplacing your keys, forgetting someone's name at a party, or coming home from the market without the most important item — these are just some of the many common memory slips we all experience from time to time.


The Memory Bible
The international bestseller that provides pioneering brain-enhancement strategies, memory exercises, a healthy brain diet, and stress reduction tps for enhancing cognitive function and halting memory loss.

Gary Small, M.D., is Director of Behavioral Health Breakthrough Therapies for Hackensack Meridian Health, and UCLA Emeritus Professor of Psychiatry and Founding Director of the UCLA Longevity Center. Dr. Small often appears on the TODAY show, Good Morning America, and CNN, and is co-author (with his wife Gigi Vorgan) of 14 popular books, including The New York Times bestseller The Memory Bible, L.A. Times bestseller The Other Side of the Couch, and 2 Weeks to a Younger Brain.

Tags: medications | depression | contraceptives | dr. small

Medications Can Worsen Depression

By    |   Thursday, 05 March 2026 04:32 PM EST

As a psychiatrist, I always consider the possibility of a drug side effect as a cause of one of the most common mental disorders I see: depression.

There’s a 15 percent chance that a person will develop clinical depression requiring medical intervention at some point in his or her life. A larger proportion develop less severe depression symptoms. Medicines for a variety of conditions can contribute to depression symptoms.

For example, a very common asthma medication, montelukast (Singulair), has been reported to not only cause depression and anxiety, but also suicidal thinking.

Certain acne treatments — such as isotretinoin (Accutane) — contain retinoic acid, an ingredient that also may lead to depression symptoms.

Other medicines that have been reported to occasionally cause such symptoms include:

• Varenicline (Chantix) helps people who want to stop smoking. Potential mental side effects include hostility, anxiety, depression, and suicidal thinking.

• Propranolol hydrochloride (Inderal), a beta-blocker blood pressure medication, can contribute to depressive symptoms.

• Contraceptives including those delivered by vaginal ring or patch can lead to depression.

 • Corticosteroids have been reported to cause not only depression, but also anxiety, panic attacks, and psychosis.

• Vigabatrin is an anticonvulsant medication that may cause depression, irritability, and psychosis.

© 2026 NewsmaxHealth. All rights reserved.


Dr-Small
As a psychiatrist, I always consider the possibility of a drug side effect as a cause of one of the most common mental disorders I see: depression.
medications, depression, contraceptives, dr. small
202
2026-32-05
Thursday, 05 March 2026 04:32 PM
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