Question: My wife went to her doctor and came home with a prescription for Prozac. She had never seemed depressed to me, but I guess she told her doctor she had been feeling blue lately. Now that she’s on the Prozac, she seems listless and without energy. If anything, she seems more depressed now. What can I do about this?

Dr. Hibberd's answer:
Prozac is used to treat mental depression, obsessive-compulsive disorder (OCD), bulimia nervosa, premenstrual dysphoric disorder (PMDD), and panic disorder. This medicine may also be used for other conditions as determined by your doctor. This medicine should come with a medication guide; read it carefully and discuss things you do not understand with your doctor.
I hope that your wife is taking this medicine only as directed by her doctor. Dosing and duration is very important with Prozac. It is possible that there could be worsening depression, other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes with Prozac.
It is important to report any changes immediately to the doctor and and to check her progress at regular visits in order to allow her doctor to make changes in her dose and help reduce any side effects. Her doctor may even order blood tests to check for unwanted effects.