Question: Are there any experts in Hughes syndrome? I know that warfarin is a treatment, and I’ve also read of Plaquenil being used to suppress the immune system to some degree and help prevent the formation of blood clots.
Dr. Hibberd's Answer:

Hughes syndrome is more commonly referred to as antiphospholipid syndrome. It was named after a rheumatologist at the London Lupus Center who works in the treatment of immune disorders, especially Lupus and Hughes syndrome.

Antiphospholipid syndrome is an immune mediated (i.e., antibody mediated) disorder of coagulation that causes blood clots in veins and arteries. It causes miscarriage, preterm labor, and severe pre-eclampsia (a serious disorder of blood pressure in pregnancy) in women.

This syndrome requires input from a hematologist (a medical doctor who specializes in disorders of the bloodstream) and is usually managed by a rheumatologist or immunologist.