Question: My brother’s creatinine level is 3.0. What can he do to prevent further deterioration of his kidney?

Dr. Hibberd's Answer:
First of all, have this test repeated. Creatinine is commonly used as a rough guide to renal function, but must be interpreted in conjunction with other factors including the BUN (blood urea nitrogen), and urinalysis for protein and creatinine clearance.
Dehydration, obstruction, and numerous renal and non-renal conditions can cause isolated elevated levels. Creatinine elevation will be seen in conditions of elevated muscle mass, though not usually to this level.
Have this elevated creatinine professionally investigated. If he is suspected of having persistent elevation or renal disease, request a referral to a specialist in kidney disease (nephrologist).