Chauncey W. Crandall, M.D., F.A.C.C.

Dr. Chauncey W. Crandall, author of Dr. Crandall’s Heart Health Report newsletter, is chief of the Cardiac Transplant Program at the world-renowned Palm Beach Cardiovascular Clinic in Palm Beach Gardens, Fla. He practices interventional, vascular, and transplant cardiology. Dr. Crandall received his post-graduate training at Yale University School of Medicine, where he also completed three years of research in the Cardiovascular Surgery Division. Dr. Crandall regularly lectures nationally and internationally on preventive cardiology, cardiology healthcare of the elderly, healing, interventional cardiology, and heart transplants. Known as the “Christian physician,” Dr. Crandall has been heralded for his values and message of hope to all his heart patients.

Tags: fibroblast growth factors | cancer | blood pressure
OPINION

Cancer Drugs Control BP

Chauncey Crandall, M.D. By Tuesday, 25 February 2020 04:33 PM EST Current | Bio | Archive

Drugs designed to halt cancer growth may offer a new way to control high blood pressure. In one study, Georgetown University Medical Center researchers found that manipulating fibroblast growth factors (FGFs), could offer insights for developing new drugs to lower blood pressure.

The study focused on a protein called FGGBI, which modulates FGFs. The gene that regulates FGF is known as FGF binding protein 1 (FGFBP1).

Using a mouse model in which FGFBP1 can be switched on or off, the researchers noted that switching it made blood pressure rise.

“The reading actually went up [30 mmHg] from a normal blood pressure to pretty hypertension,” said lead author Dr. Anton Wellstein, adding, “It was amazing.”

“It’s rare that a single class of drugs can be used for such different conditions, but that is what our study strongly suggests,” he added, referring to the study, which is published in the journal Hypertension.

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Dr-Crandall
Drugs designed to halt cancer growth may offer a new way to control high blood pressure.
fibroblast growth factors, cancer, blood pressure
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2020-33-25
Tuesday, 25 February 2020 04:33 PM
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