Your liver is very sensitive to stress. But what exactly stresses a liver?

A high-fat diet is one major cause. Research out of MIT shows that when liver cells feel imperiled by excess fat, they revert to an immature state that helps them survive — but also makes them more likely to become cancerous.

A healthy liver doesn't contain a lot of fat. But when it builds up to 5%-10%, you get health problems such as fatty liver disease (now called MASLD), which increases the risk of liver cancer.

And even today, the overall five-year survival rate for liver cancer is only around 20% — 38% for a localized condition, and as low as 4% if it has spread.

How can you help your liver live long and prosper?

• Wash produce/buy organic and avoid toxins in household cleaning products, gardening supplies, and foods (yes, some additives are toxic).

• Be aware of potential side effects from medications and supplements/herbs — many are contaminated. Since 2000, there's been an 800% increase in herbal and dietary supplement-related liver failure in the U.S.

• Drink moderately or abstain altogether.

• Avoid added sugars and syrups, which quickly convert to fat in the liver.

• Prevent hepatitis A, B, and C by getting vaccinated, practicing safe sex, and washing hands frequently.

• Coffee is good for your liver; if you like it, continue to enjoy.