Israel’s attorney general has ordered police to open an investigation into Prime Minister Benjamin Netanyahu’s wife on suspicion of harassing political opponents and witnesses in the Israeli leader’s corruption trial.

The Israeli Justice Ministry made the announcement in a terse message late Thursday, saying the investigation would focus on the findings of a recent report by the “Uvda” investigative program into Sara Netanyahu.

The program uncovered a trove of WhatsApp messages in which Mrs. Netanyahu appears to instruct a former aide to organize protests against political opponents and to intimidate Hadas Klein, a key witness in the trial.

The announcement did not mention Mrs. Netanyahu by name, and the Justice Ministry declined further comment.

But in a video released earlier Thursday, Netanyahu listed what he said were the many kind and charitable acts by his wife and blasted the Uvda report as “lies.”

It was the latest in a long line of legal troubles for the Netanyahus — highlighted by the prime minister's ongoing corruption trial.

Netanyahu is charged with fraud, breach of trust and accepting bribes in a series of cases alleging he exchanged favors with powerful media moguls and wealthy associates. Netanyahu denies the charges and says he is the victim of a “witch hunt” by overzealous prosecutors, police and the media.