KINSHASA, Congo (AP) — Congo's year-long Ebola outbreak has spread to a new province, with two cases confirmed in South Kivu, according to the government health ministry.

Two new patients have tested positive in the Mwenga area of South Kivu, adding to North Kivu and Ituri provinces where there are confirmed cases of the disease, according to the health ministry.

The Ebola outbreak in eastern Congo has killed 1,808 people out of 2,765 confirmed cases, according to the new report. The current outbreak, which started on Aug. 1 last year, is the second largest in history.

The spread of confirmed cases to a third province shows that health workers have struggled to contain the outbreak, despite the use of a vaccine. Many people in eastern Congo do not trust doctors and other medics.