Is Leaky Gut Responsible for Increased Risk of Cancer?

Having a leaky gut may result in an increased risk of some cancers, studies indicate.

Leaky gut syndrome occurs when the lining of the intestines is inflamed and unable to absorb the nutrients that are necessary for healthy functioning. Additionally, it may allow bacteria, toxins, and undigested food particles to enter into the bloodstream, Cancer Compass said.

Science Daily reported one study showed that without the hormone receptor guanylyl cyclase C, the intestinal linings weaken. This receptor has been identified as a tumor suppressor and has an important job of strengthening the intestines.

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Health Now Medical Center said innate lymphoid cells produce the interleukin-22 hormone that fights against foreign bacteria, promotes growth of good bacteria, and heals wounds of gut tissues. Good bacteria help keep bad genes and the diseases that result from them — including cancer — in check. The lymphoid cells also help to heal cancerous lesions in the gut.

With leaky gut syndrome, the toxins that enter the bloodstream will go to the liver to be filtered, but because of the increase in foreign invaders, the organ may not be able handle them all. In effect, toxins may enter into cells and cause genetic mutations. Such mutations may lead to the development of cancerous cells, according to Functional Medicine University.

Additionally, with a weaker barrier between the gastrointestinal tract and the bloodstream, muscle tissue toxicity may become a problem, according to DrKaslow.com. In this instance, microbes grow and inflammation can occur, leading to joint pain and decreases in energy production. As a result, fibromyalgia, arthritis, and even cancer could develop.

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Functional Medicine University said antibiotics destroy bacteria living in the intestines, and may contribute to the development of leaky gut syndrome, resulting in an increased risk of colon cancer.

DrKaslow.com added that due to the decrease in healthy bacteria from the small intestines, increased amounts of bile from the liver enter into the large intestines, which may also promote colon cancer.

Treatments of cancer, such as chemotherapy, may lead to an increase in permeability of the intestinal lining, as well, according to Natural Medicine Journal.

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