Celebrex is used for the treatment of rheumatoid arthritis and osteoarthritis, two common forms of arthritis. The drug works to relieve inflammation, joint pain, stiffness and swelling, but it is not a cure for the disorder,
the Johns Hopkins Arthritis Center noted.
Celebrex is a nonsteroidal anti-inflammatory drug (NSAID). Side effects of NSAIDs include upset stomach and ulcers, but Celebrex is less likely to cause these symptoms, although some patients have complained of stomach problems, indigestion and diarrhea, the center said.
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The medication helps to reduce pain and swelling enough for arthritis sufferers to perform normal daily routines,
according to WebMD. It does this by blocking prostaglandins, enzymes in the body that cause the pain and swelling.
Other NSAIDs work the same way, but also block the prostaglandins from protecting the stomach lining against digestive fluids. Celebrex focuses on the enzyme responsible for pain and inflammation without playing a role in the enzyme that protects the stomach lining. So Celebrex is less likely than other NSAIDs to cause stomach damage,
the Arthritis Foundation reported.
As with all NSAIDs, Celebrex may increase the risk of heart disease, heart attack or stroke in rare cases,
according to MedicineNet.com. People with a family history of heart disease, high blood pressure or diabetes should consult with their doctor before taking the drug.
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Risks may increase with the long-term use of Celebrex. The drug may be safer for people who take it intermittently, but in some cases arthritis patients may have to weigh the risks with the benefit Celebrex provides for pain relief, the Arthritis Foundation pointed out. The foundation noted that people with rheumatoid arthritis and other chronic conditions, such as obesity or diabetes, already have increased risks of developing heart disease.
A smaller dose may help avoid the risk if it relieves pain
People should seek their doctor’s advice about using Celebrex if they are taking other prescription drugs, non-prescription medicine, vitamins and herbal supplements, which might interact with the drug, Johns Hopkins Arthritis Center explained.
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