Trump Wednesday tapped Gail Slater, an antitrust veteran and JD Vance economic adviser, to lead the Department of Justice's antitrust division and take charge of a full docket of blockbuster monopoly cases against Google, Visa, Apple, and others.

"Big Tech has run wild for years, stifling competition in our most innovative sector and, as we all know, using its market power to crack down on the rights of so many Americans, as well as those of Little Tech!" Trump wrote in a post on his social media platform.

"I was proud to fight these abuses in my First Term, and our Department of Justice’s antitrust team will continue that work under Gail’s leadership," he wrote, adding that she would also "ensure that our competition laws are enforced, both vigorously and FAIRLY, with clear rules that facilitate, rather than stifle, the ingenuity of our greatest companies."

Vance has said antitrust enforcers should take a broader approach to antitrust enforcement, and praised the work of FTC Chair Lina Khan.

Slater will take over a number of high profile cases accusing some of the world's largest companies, including Alphabet's Google, of illegally building and protecting monopolies.