Tags: Coronavirus | pandemic | men | women | morbidity | covid | 19

Men Get Sicker, More Likely to Die of COVID-19, Data Shows

hospital workers in ppe wheel a coronavirus patient from ambulance
Health workers walk with a patient outside of Mount Sinai Hospital which has seen an upsurge of coronavirus patients on April 04, 2020 in New York City.  (Photo Spencer Platt/Getty Images)

By    |   Sunday, 05 April 2020 09:13 AM

Across the globe, the coronavirus pandemic is killing more men than women, and U.S. states that report COVID-19 deaths by gender reveal the same, according to The Washington Post.

New York City, now the world epicenter of the outbreak, has seen 55% of the cases being men, 59% of the hospitalizations, and 62% of the deaths, per the report.

"It seems there are more men coming in with really severe illness," Mount Sinai Morningside hospital emergency doctor Kaedrea Jackson told the Post. "In general, I've seen more male patients. And when they do come in, they are at a sicker state."

Among the underlying health conditions tied to serious to critical cases are age, hypertension, diabetes, cancer, and those with compromised immune systems, according to health experts. Men live an average of five years less than women and have a higher probability to suffer from those conditions, per the World Health Organization, the Post reported.

"I've seen more males that need immediate respiratory support — to be intubated or supplemental oxygen," Jackson told the Post. "That's been the major difference. They come in sicker."

But, she added, "I don't think there’s anything that's very clear that shows me the etiology of why it's been more males."

In other states in the U.S., there are slightly more women infected with COVID-19 than men – althougha factor could be that women are more health conscious and more likely to get tested.

"Women generally are more likely to seek care than men are," Kent State University epidemiologist Tara Smith told the Post. "So this could just be a bias in that aspect: As a gender, we're just more likely to go see a doctor when we're sick, so we're more likely to have a test done in the first place."

Still, more men die from the coronavirus in states that report deaths by gender, according to the Post.

Scientists have reported women have more effective immune systems, tied to the hormones and genes of their two X chromosomes – which might explain why men have been more likely to have serious cases and die, the Post reported.

"There's probably something written in their DNA that we just don't know or understand yet," Hawkins told the Post.

Females have shown stronger immune systems in many animals, including humans, according to Robyn Klein, director of the Center for Neuroimmunology and Neuroinfectious Diseases at Washington University in St. Louis, per the Post.

"With regard to viral infection, it's been very well established that females have much stronger immune responses than males," Klein told the Post. "Not just as a result of exposures or behavior. But there are actual differences in the ways that immune cells respond."

Biologically, testosterone is known to tamp down inflammation, while estrogen can bind to immune cells and activate the disease fighters, per the report.

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Across the globe, the coronavirus pandemic is killing more men than women, and U.S. states that report COVID-19 deaths by gender reveal the same, according to The Washington Post.New York City, now the world epicenter of the outbreak, has seen 55% ...
pandemic, men, women, morbidity, covid, 19
Sunday, 05 April 2020 09:13 AM
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