Lake-effect snow caused a 50-car pileup on Interstate 90 east of Cleveland, Ohio, on Thursday, shutting down the road for 14 hours and injuring about 20 people, at least three seriously.
A Greyhound bus and more than a dozen trucks started the chain reaction crash near the Ohio-Pennsylvania border. Highway crews spent the night removing vehicles and assisting injured drivers and passengers before reopening the roadway on Friday morning.
The crash involved both east and westbound lanes of the highway between Route 44 and Vrooman Road.
According to Fox8 News, Greyhound bus passenger Greg Carmichael was headed home to Buffalo when the bus was hit from behind by a semi-tractor trailer. Several people on the bus were seriously injured, and the crash began the domino effect that eventually totaled 50 vehicles, Carmichael told the station.
Another weather-related pileup involving about 40 vehicles took place near Fowlerville, Michigan, on Thursday morning that left three dead and 11 injured.
Much of the country is being affected by an arctic blast of air that has led to subzero temperatures in several states as well as significant snow and ice accumulation.
The snow around the Great Lakes is expected to continue into Saturday due to a Canadian air mass that has moved south over still-warmer waters, according to the National Weather Service. Snow may be locally heavy along with wind gusts that could cause drifting and blowing.
More cold air and snow is expected next week as the polar vortex shifts.
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