Tags: Study: | Added | Fructose | Leads | Fat

Study: Added Fructose Leads to Fat

Thursday, 15 December 2005 12:00 AM

Fructose, the sugar found in the corn-syrup sweeteners used in many processed foods, may trick the body into thinking it's hungrier than it really is, causing people to eat more and risk becoming obese.

That's the disturbing finding of a group of University of Florida researchers who believe it may help explain why there is a growing obesity epidemic in America Today.

Dr. Richard Johnson and his colleagues identified fructose as part of a biochemical process that leads to weight gain and other precursors of Type 2 diabetes. They also found that fructose causes an increase in blood uric acid that can block the action of insulin, the hormone that regulates how body cells use and store the sugar they need for energy.

If increased uric acid levels occur frequently enough, features of metabolic syndrome - obesity, elevated blood cholesterol levels and high blood pressure - may develop.

The Florida researchers fed rats a high-fructose diet for 10 weeks. All the rats experienced an increase in uric acid in the bloodstream and also went on to develop insulin resistance.

"When we blocked or lowered uric acid, we were able to largely prevent or reverse features of the metabolic syndrome," said Dr. Johnson, professor of nephrology and chief of nephrology, hypertension and transplantation at the university's College of Medicine.

"We were able to significantly reduce weight gain, we were able to significantly reduce the rise in the triglycerides in the blood, the insulin resistance was less and the blood pressure fell."

The research appears in the December issue of the journal Nature Clinical Practice Nephrology and in the online edition of the American Journal of Physiology-Renal Physiology.

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Fructose, the sugar found in the corn-syrup sweeteners used in many processed foods, may trick the body into thinking it's hungrier than it really is, causing people to eat more and risk becoming obese. That's the disturbing finding of a group of University of Florida...
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2005-00-15
Thursday, 15 December 2005 12:00 AM
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