Tags: Experimental | Drug | Cuts | Heart | Attack | Damage

Experimental Drug Cuts Heart Attack Damage

Wednesday, 26 April 2006 12:00 AM

An experimental drug is able to block an inflammatory protein and reduce the damage and scarring caused by heart attacks, according to British investigators.

The drug, as yet unnamed, blocks the action of C reactive protein (CRP), the inflammatory substance in the body produced during and after heart attacks, that causes much of the actual damage of heart attacks.

"By blocking the protein we reduce the extent of damage in a heart attack, and that in turn reduces the size of the scar," said Dr. Mark Pepys, of University College London, who headed the research team. "Reducing the immediate damage is thus critically important."

In animal studies, Pepys and his team found the drug reduced CRP's ability to harm tissue and yet produced no serious side effects.

He said human tests may begin within a year.

"The drug would be given as soon as patients arrived in hospital. If effective, it would reduce the amount of damage in the heart, thus limiting early mortality and the size of the scar left in the heart," Pepys said.

The study appears in the journal, Nature.

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An experimental drug is able to block an inflammatory protein and reduce the damage and scarring caused by heart attacks, according to British investigators. The drug, as yet unnamed, blocks the action of C reactive protein (CRP), the inflammatory substance in the body...
Experimental,Drug,Cuts,Heart,Attack,Damage
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2006-00-26
Wednesday, 26 April 2006 12:00 AM
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