Tags: dementia | cancer | colon | statin | ampakine

Help for Dementia Sufferers

Tuesday, 13 May 2014 04:35 PM Current | Bio | Archive

Q: My wife has dementia. I recently ran across the word “ampakine” in searching for help. Can you tell me what this is?
— James P., Oxnard, Calif.
A: Ampakines are a class of drugs that have been shown to improve short-term memory in animal testing and limited human testing. They appear to have a fairly good safety record, but have not been studied extensively.
They work by two methods. First, the drugs improve critical signaling between special types of brain cells called AMPA glutamatergic neurons.
Second, but more importantly, ampakines increase the brain’s production of two powerful substances — BDNF and NGF— that are known to repair the brain and enhance memory.
If your wife’s problem began after taking a statin, the most likely source of the problem is a deficiency in CoQ10, which is very common with these dangerous drugs. Lowering cholesterol in the elderly is very harmful to the brain, and studies have shown that lowering cholesterol in elderly women does not reduce the risk of heart attacks or strokes and impairs brain function — especially memory.
For more information, see my previous newsletters on statins. I have seen a number of people get better taking CoQ10 in high doses — 300 to 600 mg, three times a day.
Q: What supplements might be most beneficial for someone with colon cancer?
— Don N., Rochester, N.Y.
A: An impressive amount of research is showing that curcumin, quercetin, ellagic acid, N-butyrate, and DHA (docosahexaenoic acid) can inhibit colon cancers. They also all enhance the effectiveness and reduce the side effects of chemotherapy — that is, they kill cancer cells and protect normal cells.
There is a very strong connection between colon cancer invasion and growth and glutamate intake. Glutamates (such as hydrolyzed proteins and soy proteins) are found in most processed foods.
Fresh foods, especially vegetables, are essential to reduce cancer growth. White tea contains a number of anticancer compounds — even three cups of strong white tea a day supplies these cancer-fighting chemicals.
Avoiding excess iron is essential as well. For more details on fighting cancer, see my book “Natural Strategies for Cancer Patients.”
Q: Doctors often say that once you start taking statins you can’t stop the therapy. Do you think someone can come off statins once he/she has started them?
— Stavros G., Limassol, Cyprus
A: I hear this all the time, and it never makes sense. Do doctors tell you that before you take the drug that you will not be able to stop it? I doubt it.
But there’s really no need to take statins. Compelling evidence shows that the death rate reduction offered by statins is something like 0.1 percent — in other words, no different than taking an aspirin a day. Most studies confirm that statins have no beneficial effects for the first year or so of taking them, so stopping them would then have no acute effects.
One can take an aspirin a day until they are on a full program of heart health nutrition as discussed in my previous newsletter on heart health. Curcumin, quercetin, natural vitamin C, resveratrol, ellagic acid (from pomegranate juice or extract), and omega-3 oils have all shown far greater effects in preventing atherosclerosis and even reversing it than any known statin drug. In combination they are even more powerful.
Most doctors never tell their patients of the severe side effects of these drugs. Avoiding sugar and high-carbohydrate diets is more important than any low-fat diet and most drugs.

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Q: My wife has dementia. I recently ran across the word “ampakine” in searching for help. Can you tell me what this is? — James P., Oxnard, Calif.
dementia, cancer, colon, statin, ampakine
Tuesday, 13 May 2014 04:35 PM
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