​These are the five key areas that need to be treated for fatigue and pain to resolve:

1. Sleep. Because the hypothalamic "circuit breaker" that is offline controls sleep, most patients need a mix of natural and prescription sleep treatments. For you to get well and pain free, it is critical that you take enough of the correct natural and prescription sleep treatments to get eight to nine hours sleep at night. I recommend starting with natural therapies and supplements.
    
2. Hormonal deficiencies. The hypothalamus is the main control center, via the pituitary gland, for most of the glands in the body. Most of the normal ranges for our blood tests were not developed in the context of hypothalamic suppression or these syndromes. Because of this (and for a number of other reasons) it is usually necessary to treat with natural thyroid, adrenal, and ovarian and testicular hormones ― despite normal blood tests. These hormones have been found to be reasonably safe when used in low doses. Low thyroid, which reflects as fatigue, weight gain, cold intolerance and even unexplained infertility, is especially common, and the majority of those who benefit from thyroid have normal lab tests, so treatment trial should be given (using natural thyroid hormones) if symptoms are suggestive.
    
3. Infections. Many studies have shown immune system dysfunction in chronic fatigue syndrom, which can result in many unusual infections. These include many different viral infections, parasites, and other bowel infections, antibiotic sensitive infections, and, most importantly, fungal/Candida infections. 
    

4. Nutritional supplementation. Widespread nutritional deficiencies are common, and require dozens of nutrients. I recommend a good daily multivitamin. Ribose supplementation should also be taken as it can powerfully jump start your energy. In our initial study, ribose increased energy an average of 45 percent in just three weeks.
    

5. Exercise. Start by walking as long as you comfortably can (even if that is only two minutes). After 10 weeks on treatment, start to increase your walks by up to one minute more each day as able. When you are up to an hour of walking, you can increase intensity.