Tags: Cancer | tumeric | curcumin | thalidomide | cancer | destroy

Tumeric Spice, Nausea Drug Destroy Cancer Cells: Study

By    |   Wednesday, 21 August 2013 04:43 PM

A compound found in the spice turmeric, when combined with a common anti-nausea drug, has been found to destroy cancers cells in the lab.
In a study published in the journal Organic & Biomolecular Chemistry, Virginia Commonwealth University Massey Cancer Center researchers found the one-two punch delivered by curcumin — an active ingredient in the common kitchen spice — and the drug thalidomide effectively creates hybrid molecules that kill multiple myeloma cells.
"Although thalidomide disturbs the microenvironment of tumor cells in bone marrow, it disintegrates in the body," said lead researcher Shijun Zhang, assistant professor in the Department of Medicinal Chemistry at the VCU School of Pharmacy. "Curcumin, also active against cancers, is limited by its poor water solubility. But the combination of thalidomide and curcumin in the hybrid molecules enhances both the cytotoxicity and solubility."
Editor's Note: Video Exposes Dangers of Obamacare Law

Thalidomide was used in the 1950s to help control morning sickness, but was taken off the shelves in 1962 after it was found to cause birth defects. In the 1990s the drug was re-introduced as a treatment for multiple myeloma. Turmeric has long been used in herbal remedies and is being studied as a potential weapon against cancer, arthritis and Alzheimer's disease.
The VCU researchers found the hybrid molecules of turmeric and thalidomide created more created two compounds that effectively induced cancer cells to self-destruct.
"Overall, the combination of the spice and the drug was significantly more potent than either individually, suggesting that this hybrid strategy in drug design could lead to novel compounds with improved biological activities," said co-researcher researchers Steven Grant, M.D.

"The results also strongly encourage further optimization of [these] compounds … to develop more potent agents as treatment options for multiple myeloma."

© 2020 NewsmaxHealth. All rights reserved.

1Like our page
A compound found in the spice turmeric, when combined with a common anti-nausea drug, has been found to destroy cancers cells in the lab.
Wednesday, 21 August 2013 04:43 PM
Newsmax Media, Inc.
Newsmax TV Live

The information presented on this website is not intended as specific medical advice and is not a substitute for professional medical treatment or diagnosis. Read Newsmax Terms and Conditions of Service.

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

© Newsmax Media, Inc.
All Rights Reserved