Tags: testosterone | therapy | fat

Testosterone Therapy Sheds Pounds

Tuesday, 26 June 2012 01:58 PM

Chalk up another health benefit to testosterone therapy. New research has found men deficient in the male hormone who received replacement therapy achieved major weight loss – a benefit that came as a surprise even to researchers.
The study, presented at The Endocrine Society's 94th Annual Meeting in Houston, is the first to show testosterone therapy can significantly affect weight loss as well as body composition.
"The substantial weight loss found in our study — an average of 36 pounds — was a surprise," said lead researcher Farid Saad, with Bayer Pharma, which makes a brand of testosterone therapy and helped fund the study.
Although prior research has shown testosterone therapy can produce changes in body composition, such as increased lean mass and decreased fat mass, Saad said the net effect on weight seemed unchanged in those studies. But the new study, involving 255 German men, had a longer follow-up by at least two years and used long-acting injections of testosterone.
The study participants, whose average age was nearly 61, received treatment for up to five years. They did not follow a controlled diet or standard exercise program but received advice to improve their lifestyle habits.
On average, the men weighed 236 pounds before beginning testosterone treatment and 200 pounds after treatment, the researchers reported. In addition, the men lost an average of nearly 3.5 inches around their waist.
In the study, treatment used a slow-release, injectable form of testosterone undecanoate that is not yet available in the United States. It is marketed in Europe, Latin America, Australia and parts of Asia and Africa.
"These results are encouraging because studies show that weight loss drugs and lifestyle interventions have been largely unsuccessful, especially long term," Saad said.
Testosterone deficiency becomes more common with age, and many middle-aged men with low levels of the hormone are obese.
Testosterone replacement is the standard treatment for men with symptomatic testosterone deficiency, according to The Endocrine Society guidelines.

© HealthDay

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Men who get injections of the male hormone experience major weight loss.
Tuesday, 26 June 2012 01:58 PM
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