Tags: statin | pancreatitis | risk

Statins Tied to Lower Pancreatitis Risk

Thursday, 23 August 2012 10:02 AM

The use of cholesterol-lowering statin drugs may reduce the risk of pancreatitis in patients with normal or mildly elevated triglyceride levels, according to a new analysis published in the Journal of the American Medical Association.
The finding, which is based on a review of multiple studies involving more than 150,000 people, breaks with past research that has suggested the use of lipid-lowering statins may increase the risk of pancreatitis.
For the study, led by Dr. David Preiss of the University of Glasgow, researchers examined more than 20 published and unpublished studies of the associations between use of a statin or a fibrate and the incidence of pancreatitis.
When the study results were combined, researchers found patients taking statins had a 21 percent lower risk of developing pancreatitis than those receiving standard care or taking an inactive placebo.
"In [patients] with slightly elevated triglyceride levels, statins appear better supported by the available data … for preventing pancreatitis,” the researchers concluded. “Lifestyle modifications also remain important to improve lipid profiles in such individuals. In patients with severe hypertriglyceridemia, a trial comparing fibrates and statins for preventing pancreatitis would be clinically valuable."

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The use of cholesterol-lowering statin drugs may reduce the risk of pancreatitis.
Thursday, 23 August 2012 10:02 AM
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