Tags: prostate | cancer | test | psa

Novel Method Diagnoses Prostate Cancers

Monday, 13 Aug 2012 10:51 AM

A new prostate cancer test uses the combined power of a novel drug therapy and changes in PSA levels to identify men likely to have aggressive tumors despite negative biopsies.
A report on the new technique, reported by researchers at New York-Presbyterian Hospital/Weill Cornell Medical Center, said PSA – prostate-specific antigen – can be a much more effective marker for prostate cancer when an additional drug therapy is used. The PSA screening is now used a stand-alone screening.
"At a time when the value of PSA is being increasingly debated, we have shown that when used in a specific way, it can be of great value in identifying men with previously undetected prostate cancer," said Dr. Steven A. Kaplan, who led the study published in the Journal of Urology.
SPECIAL: This Small Group of Doctors are Quietly Curing Cancer — Read More.
"We have shown that using PSA with these drugs can help us differentiate prostate cancer from benign prostate disease in patients who are difficult to diagnose. It also demonstrates a better way to use both the PSA test and these powerful drugs."
Kaplan developed the combination screening method as a way to understand cancer risk in men who have consistently abnormal PSA readings despite having negative biopsies. He noted the PSA test alone is not a good indicator of prostate cancer. "It measures multiple factors associated with prostate disease,” he said, “including enlargement of the prostate and inflammation."
But the new research, involving 276 men, found the use of two drugs used to treat enlarged prostate – finasteride and dutasteride – improved the usefulness of PSA in diagnosing cancer. Kaplan’s team found patients whose PSA levels remained high after their prostates had been shrunk were more likely to have aggressive forms of cancer.
"Our study shows these drugs may be most helpful in helping us diagnose undetectable prostate cancer," Kaplan said.
SPECIAL: This Small Group of Doctors are Quietly Curing Cancer — Read More.

© HealthDay

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A new prostate cancer screening method uses the combined power of a drug therapy and changes in PSA levels.
Monday, 13 Aug 2012 10:51 AM
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