Tags: oral | spray | flu | cold | germ

Oral Spray Shown to Fight Cold, Flu Germs

Tuesday, 11 September 2012 11:06 AM

It sounds too good to be true, but a team of Cleveland hospital scientists has developed a new germ-killing oral spray that has been found to be effective against cold and flu viruses.
University Hospitals Case Medical Center researchers, who reported the advance at the Interscience Conference on Antimicrobial Agents and Chemotherapy in San Francisco this week, said the so-called Halo Oral Antiseptic spray could provide a new “one-two punch” to prevent cold symptoms and influenza.
"Respiratory tract disease is a major cause of morbidity and mortality throughout the world," said Dr. Frank Esper, an infectious disease expert at UH Rainbow Babies & Children's Hospital who presented details on the spray’s effectiveness in studies. "Yet there has been limited progress in the prevention of respiratory virus infections. Halo is unique in that it offers protection from airborne germs such as influenza and rhinovirus."
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Esper said the research team found the first-of-its kind Halo spray killed 99.9 percent of infectious airborne germs. He said the product is now available on store shelves.
Esper said Halo uses several compounds – including glycerine and xanthan gum as a microbial barrier, combined with cetylpyridinium chloride (CPC) as a broad-spectrum anti-infective agent – to fight respiratory illnesses. His team tested the product against clinical strains of 2009 swine flu virus to demonstrate its anti-infective activity in cell culture assays.
"The glycerine and xanthan gum prevent the germs from entering a person's system and the CPC kills the germs once they're trapped there," he said.
A second study, presented by Mahmoud Ghannoum of UH Case Medical Center, showed it proved effective against disease-causing germs that cause colds as well as 11 clinical strains of whooping cough (Bordetella pertussis) against which the spray was tested.
The results showed that when a person used three sprays of Halo, it destroyed airborne germs breathed in for up to six hours, even when people were eating and drinking. The concept of coating the back of the oral cavity to prevent germs from entering and then providing sustained antiseptic action to kill airborne germs was developed by a Cleveland company, Oasis Consumer Healthcare.
"Exposure to airborne germs is inevitable – especially in crowded environments and when traveling," said Ghannoum. "Unlike other products that support the immune system or protect from germs on surfaces or hands, Halo is the first and only product of its kind to offer protection from airborne germs."
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A new germ-killing oral spray has been developed that is effective against cold and flu viruses.
Tuesday, 11 September 2012 11:06 AM
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