Tags: myelodysplasticsyndrome | blood | cancer | symptom

What Causes Myelodysplastic Syndrome?

Thursday, 03 April 2014 02:09 AM

Myelodysplastic syndrome is a type of cancer in which the bone marrow is no longer capable of producing healthy blood cells while producing unhealthy blast cells in the body.
In a healthy person, the bone marrows make immature cells that mature in time. The cells then become lymphoid cells or myeloid cells. They respectively form white blood cells or red blood cells, platelets, and white myeloid cells.

In a person suffering from myelodeysplastic syndrome, the immature cells do not become healthy blood cells (red or white) or platelets. They lead to the formation of blasts, which either die in the bone marrow or dissolve in the blood to cause cancer.
The cancer may be diagnosed by a physical examination, in case any symptoms persist. Bone marrow analysis and genetic analysis may be done by the specialist to diagnose myelodeysplastic syndrome.

Causes and Types of Myelodeysplastic Syndrome

The causes of cancer are difficult to determine. However, there are certain specific types of myelodysplastic syndrome, which may depend on the following factors:
  • It depends on what kind of cells is affected. It may be a specific type of blood cells or more than one type of blood cells that cause cancer.
  • It may depend on the number of blasts in the bone marrow causing cancer.
  • It may also depend on the type of genetic material in the bone marrow leading to myelodeysplastic syndrome.
  • Other factors include the stage at which the cancer is diagnosed or how many blasts are in the bone marrow.

Possible Signs and Symptoms of Myelodeysplastic Syndrome

Often, there is a general category of symptoms entailing myelodysplastic cancer, which may not be evident at an early stage but with time become serious and visible. The symptoms are as follows:
  • Fatigue by anemia is a prominent symptom. It means lack of red blood cells in the body causing myelodeysplastic syndrome
  • Unusual bleeding is another common symptom. Bleeding through the nose is a visible symptom that might occur
  • Bruises and tiny red marks under the skin is a visible symptom, which is most easily diagnosed
  • Paleness and shortness of breath during physical activity are other symptoms that patients of myelodeysplastic syndrome may experience


Some essential steps in the prognosis and treatment of myelodysplastic syndrome and its symptoms include the following:
  • Chemotherapy
  • Drugs, antibiotics, and transfusion of blood
  • Treatments to reduce iron levels
  • Stem cell transplant—this method may be the last step if all other treatments fail. A stem cell transplant could cure the cancer completely as it leads to the replacement of bone marrow cells. It is also called a bone marrow transplant and effectively treats all symptoms of myelodeysplastic syndrome. These new cells then would start producing new and healthy cells in the body

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Myelodysplastic syndrome is a particular type of cancer affecting the production of healthy blood cells in the body. It is treatable and curable, provided it is detected on time.
Thursday, 03 April 2014 02:09 AM
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