Tags: frog | skin | antibiotics

Frog Skin Contains Natural Antibiotics

Monday, 17 December 2012 12:08 PM

A traditional Russian folk practice for keeping milk from going bad — by placing a frog in the milk bucket — has led modern-day scientists to discover a wealth of natural antibiotic substances in the skin of a common frog.
The finding, published in American Chemical Society’s Journal of Proteome Research, suggests the natural defenses of the Russian Brown Frog may offer clues to a new line of antimicrobial agents for use in fighting infections.
The research, led by A. T. Lebedev and colleagues, determined amphibians secrete antimicrobial substances called peptides through their skin as a defense against bacteria and other microorganisms that thrive in the wet places frogs, toads, and salamanders live.
Previous research identified 21 substances on the skin of the Russian Brown Frog with antibiotic properties. But Lebedev's team determined the frog’s skin contains 76 additional antimicrobial substances with potential medical applications.
In lab tests, they found the substances were as effective in killing Salmonella and Staphylococcus bacteria as some prescription antibiotic medicines.
"These peptides could be potentially useful for the prevention of both pathogenic and antibiotic resistant bacterial strains while their action may also explain the traditional experience of rural populations," the scientists concluded.

© HealthDay

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Scientists, studying a Russian folk remedy, discover a wealth of antibiotic substances in the skin of a common frog.
Monday, 17 December 2012 12:08 PM
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