Tags: diabetic | drug | weight | loss

Drug Helps Diabetics Slim Down

Thursday, 28 Jun 2012 02:03 PM




An experimental new weight-loss drug has been found to help overweight patients with diabetes shed a significant number of pounds.
The findings, presented at The Endocrine Society's 94th Annual Meeting in Houston this week, suggest the new drug — phentermine/topiramate — could be an effective new weapon in the battle against the nation’s obesity epidemic.
"This new medication is promising because of the amount of weight loss it produces, the resultant improvement in important risk factors for diabetes, and, particularly in the lower dose studied, in its tolerability," said lead researcher Dr. Donna H. Ryan, with the Lousiana State University’s Pennington Biomedical Research Center in Baton Rouge.
Ryan and her colleagues found patients who took the drug, along with making improvements to their diet and exercise regimens, were more likely to lose moderate amounts of weight than those who received a sugar-pill placebo and changed their diet and exercise habits.
About 14 percent of the patients who took low doses of the drug – and 31 percent who took high doses -- lost more than 10 percent of their body weight and lowered the blood pressure and glucose levels, compared to just 4 percent who received a placebo.
The new drug is a combined medication that works by decreasing appetite. The study involved more than 350 patients with type 2 diabetes. Participants' average age was 53 years, most were women, white, and their average weight was 222 pounds.
VIVUS, the company that developed phentermine/topiramate, funded the study.

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A new weight-loss drug helps overweight diabetics shed a significant number of pounds.
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2012-03-28
Thursday, 28 Jun 2012 02:03 PM
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