Tags: colon | cancer | switches

'Master Switches' for Colon Cancer?

Monday, 16 Apr 2012 01:21 PM


Case Western Reserve geneticists have discovered a discovered a set of what they described as “master switches” for genes that appear to be key to the development of colon cancer.
Researchers called the finding, reported in the journal Science, “a breakthrough” that provides a new understanding of the processes involved in the cancer’s development that could one day lead to better diagnosis and treatment.
For the study, researchers focused on segments of DNA located between genes to find the cancer switches, which they call “Variant Enhancer Loci (VELs).
"What is particularly interesting is that VELs define a 'molecular signature' of colon cancer. Meaning, they are consistently found across multiple independent colon tumor samples, despite the fact that the tumors arose in different individuals and are at different stages of the disease," said lead researcher Peter Scacheri. "The set of common VELs govern a distinct set of genes that go awry in colon cancer."
Researchers said they will now study whether doctors can determine if VELs can be used in “personalized medicine” techniques identify specific drugs and treatments that will be most effective for a particular patient.
The study was funded, in part, by the National Cancer Institute.


© HealthDay

   
1Like our page
2Share
Health-Wire
Scientists have discovered genetic 'switches' that can turn on the process of colon cancer development.
colon,cancer,switches
197
2012-21-16
Monday, 16 Apr 2012 01:21 PM
Newsmax Inc.
 

The information presented on this website is not intended as specific medical advice and is not a substitute for professional medical treatment or diagnosis. Read Newsmax Terms and Conditions of Service.

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

NEWSMAX.COM
© Newsmax Media, Inc.
All Rights Reserved