Tags: Health Topics | Cancer | prostate | medication | protein | inhibitor

New Drug May Lead to Prostate Cancer Cure

Diagnosis prostate cancer written in the diagnostic form and pills
(Dreamstime)

By    |   Tuesday, 05 November 2019 05:08 PM

British researchers have announced they have discovered a new class of medications that shows promise in inhibiting the growth or prostate cancer. According to Medical Daily, the experts have zeroed in on a protein that is present in aggressive prostate cancer cells. That protein is called AMACR and researchers have been aware of its ability to become highly active in all prostate cancers as well as in a number of other cancers.

The UK team was able to develop new drugs that successfully targeted and lowered the activity level of this aggressive protein. This discovery by experts from the Departments of Pharmacy & Pharmacology and Chemistry at the University of Bath may open up new pathways for research in treating a whole range of cancers, not only prostate cancer, they say.

"This means that we have some really promising avenues to explore as we work toward developing new treatments against prostate cancer, and other cancers where AMACR is involved," says Dr. Matthew Lloyd, lead author from the Department of Pharmacy & Pharmacology.

Simon Grieveson, head of research funding at Prostate Cancer UK said:

"With one man dying from prostate cancer every 45 minutes in the UK there is a desperate need to develop new and effective treatments for this disease, and that's why it's so important that we continue to find explorative studies like this. The protein AMACR has been shown to be present in larger quantities in aggressive prostate cancer cells, and this research group has successfully developed a technique to find the protein and monitor its activity. Further to this, they have now found certain compounds that can target the protein's activity in the lab, and stop cancer cells in their tracks."

In the United States, every 17 minutes a man dies from prostate cancer according to Zero Cancer.org. That is a little more than 86 deaths per day and 31,620 this year — or enough to fill an entire baseball stadium. Prostate cancer is the second leading cause of cancer death among American men and the most commonly diagnosed. While early detection saves lives, advances in treatment helps offer the best hope for living cancer free for a long time.

The new class of drugs identified by the University of Bath team is said to be 20 times more effective than existing drugs in targeting the AMACR protein, and while researchers acknowledge the development is still in its infancy, it offers hope and promise for those suffering from the dreaded disease over the coming years.

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British researchers have announced they have discovered a new class of medications that shows promise in inhibiting the growth or prostate cancer.
prostate, medication, protein, inhibitor
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2019-08-05
Tuesday, 05 November 2019 05:08 PM
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