Tags: Cancer | injection | treat | deadliest | prostate | cancer | aggressive

Injection to Treat Deadliest Type of Prostate Cancer

Injection to Treat Deadliest Type of Prostate Cancer

(Copyright iStock)

By    |   Wednesday, 09 November 2016 11:55 AM

Researchers at University College London are developing an injection that could treat the most aggressive prostate cancers without the side effects of chemotherapy or radiotherapy.


The scientists discovered that a molecule called NAALADL2 is found in higher amounts in aggressive prostate cancers. Since patients with higher levels of NAALADL2 are twice as likely to see their cancer return, the molecule is already used to gauge the risk of cancer recurrence.


More than 200,000 new cases of prostate cancer are diagnosed every year in American men, and about 40 percent of those are aggressive. But it's often difficult to distinguish which cancers are slow-growing and may need only watchful waiting, so tens of thousands of men undergo unnecessary treatment with side effects that can include incontinency, fatigue, and problems with intimacy.


Testing for NAALADL2 can help determine which cancers are fast-growing and need aggressive treatment.


The British researchers found that NAALADL2 can also be used to help guide medication directly to the cancer.


In the new study, the researchers attached the drug saporin to an antibody targeted against NAALADL2 to destroy prostate cancer cells in the lab.


"Using antibodies mounted with a toxic payload, we can exploit the fact that aggressive prostate cancer cells have more NAALADL2," said lead researcher Hayley Luxton.


"The next step is to further develop this for use in patients, which we hope can be done in a relatively short timeframe," she said.


UCL scientists are hoping to develop the injection within three years and begin testing it during the next five to 10 years.


According to the American Cancer Society, 1 in 7 men will be diagnosed with prostate cancer during their lifetimes.


More than 200,000 new cases of prostate cancer are diagnosed every year in American men, and about 40 percent of those are aggressive.


About 28,000 men die from the disease each year.
 

© 2019 NewsmaxHealth. All rights reserved.

   
1Like our page
2Share
Health-News
Researchers at University College London are developing an injection that could treat the most aggressive prostate cancers without the side effects of chemotherapy or radiotherapy. The scientists discovered that a molecule called NAALADL2 is found in higher amounts in...
injection, treat, deadliest, prostate, cancer, aggressive
309
2016-55-09
Wednesday, 09 November 2016 11:55 AM
Newsmax Media, Inc.
 

The information presented on this website is not intended as specific medical advice and is not a substitute for professional medical treatment or diagnosis. Read Newsmax Terms and Conditions of Service.

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

NEWSMAX.COM
© Newsmax Media, Inc.
All Rights Reserved