Tags: in vitro | ivf | birth rate | infant mortality | childhood

IVF Children More Likely to Develop Cancer: Study

a women holds her pregnant belly with both hands, one on top and one on bottom
(Andrew Matthews/AP)

By    |   Tuesday, 02 April 2019 11:37 AM EDT

Kids conceived via in vitro fertilization (IVF) are more likely to suffer from rare childhood cancers, new research reveals. It has been shown IVF pregnancies tend to have more difficulties, according to The National Center for Biotechnology Information, but the prevalence of cancer among children conceived through this method had not been well documented.

A team of researchers from the University of Minnesota charged, when they set out to establish the risk of childhood cancer among IVF conceived children, they found these kids had a 17 percent higher risk of developing the disease in their first decade of life.

They also noted the rate of hepatic tumors was over 2.5 times higher among IVF children.

According to Reuters:

"Children conceived by IVF were also 41 percent more likely to develop embryonal tumors of the central nervous system, which occur when embryonic cells remain in the brain after birth. So-called germ cell tumors, or malignancies in the reproductive tissue like the testicles or ovaries, were more than twice as common with IVF."

Researchers arrived at their findings by linking records of live births reported to the Society for Assisted Reproductive Technology Clinic Outcome Reporting System between 2004 and 2013 to the birth and cancer registries of 14 states, which included 66 percent of births in the U.S. and 75 percent of IVF-conceived births.

The team from Minnesota then linked the data to the cancer registries of the same states to find cancers diagnosed between 2013 and 2015 then randomly selected 10 children conceived naturally for each child conceived by IVF. While the data showed a notably higher risk of IVF children developing childhood cancer, researchers pointed out they could not establish whether this was due to the IVF itself or the parents' underlying infertility.

The research team examined data on 275,686 children conceived with IVF and 2.27 million kids conceived naturally.

While the rate of cancer was higher for children of IVF it was only slightly higher. Logan Spector, a professor in the Medical School and Masonic Cancer Center member and lead author of the study said: "Overall, these results are reassuring to parents who've had children through IVF."

The study was published in JAMA Pediatrics.

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Kids conceived via in vitro fertilization (IVF) are more likely to suffer from rare childhood cancers, according to The National Center for Biotechnology Information.
in vitro, ivf, birth rate, infant mortality, childhood
Tuesday, 02 April 2019 11:37 AM
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