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Common Medications Linked to Cognitive Decline

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Friday, 20 May 2016 12:49 PM Current | Bio | Archive

Running back Jerome "The Bus" Bettis played in the NFL for 13 seasons (including a Super Bowl win with the Steelers) and landed in the Hall of Fame — all while contending with asthma. When he had an attack in a 1997 game played in Jacksonville, Florida ("Imagine someone putting a plastic bag over your head," he said of the incident), they gave him a shot and puffs on a rescue inhaler and put him back in the game!

Like Bettis, over 24 million North Americans who deal with asthma depend on the right medication to control symptoms and get them back in the game.

These days, the right med may include the long-acting anticholinergic drug tiotropium (also prescribed for COPD). But while it may get you back in the game, it's blocking a neurotransmitter, acetylcholine, and that can bench your cognitive powers.

It's not the only commonly prescribed medication that's anticholinergic — in fact, dozens of nighttime sleep aids, older antihistamines, some antidepressants, cardio medications, drugs for urinary incontinence, and many others work to block acetylcholine.

In a recent issue of JAMA Neurology, researchers said, "The [long-term] use of AC [anticholinergic] medication was associated with increased brain atrophy and dysfunction and clinical decline. Thus, [long-term] use of AC medication among older adults should likely be discouraged if alternative therapies are available."

So if you're 60 or older, ask your doctor if your meds are anticholinergic, and whether there are alternatives that will protect your health equally well.
 

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If you're 60 or older, ask your doctor if your meds are anticholinergic, and whether there are alternatives that will protect your health equally well.
antihistamines, antidepressants, asthma, Dr. Oz
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2016-49-20
Friday, 20 May 2016 12:49 PM
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