Robert G. Silverman, DC, DACBN, DCBCN, MS, CCN, CNS, CSCS, CIISN, CKTP, CES, HKC, FAKTR

Dr. Robert G. Silverman is a chiropractic doctor, clinical nutritionist and author of, “Inside-Out Health: A Revolutionary Approach to Your Body,” an Amazon No. 1 bestseller in 2016. The ACA Sports Council named Dr. Silverman “Sports Chiropractor of the Year” in 2015. He also maintains a busy private practice as founder of Westchester Integrative Health Center, which specializes in the treatment of joint pain using functional nutrition along with cutting-edge, science-based, nonsurgical approaches.

Dr. Silverman is also on the advisory board for the Functional Medicine University and is a seasoned health and wellness expert on both the speaking circuits and within the media. He has appeared on FOX News Channel, FOX, NBC, CBS, CW affiliates as well as The Wall Street Journal and NewsMax, to name a few. He was invited as a guest speaker on “Talks at Google” to discuss his current book. As a frequent published author in peer-reviewed journals and other mainstream publications, including Integrative Practitioner, MindBodyGreen, Muscle and Fitness, The Original Internist and Holistic Primary Care journals, Dr. Silverman is a thought leader in his field and practice.

Tags: specialized pro-resolving mediators | inflammation

Stopping the Inflammatory Process

By
Thursday, 14 June 2018 04:34 PM Current | Bio | Archive

Helping a patient resolve a chronic inflammatory condition is one of the biggest challenges a holistic practitioner faces. Even when patients are very compliant with dietary and lifestyle changes, and take all the recommended supplements and medications, inflammation can stubbornly persist.

We know now that resolving inflammation is not a passive process. Rather, it’s complex and highly active and can sometimes happen slowly or even stall. Inflammation can linger long after the acute phase of the injury or illness has passed.

Without resolution, the body never truly returns to homeostasis — inflammation becomes chronic.

A super-family of naturally occurring lipid mediators called specialized pro-resolving mediators (SPMs) plays a crucial role in switching off the inflammatory response.

SPMs don’t block the initial inflammation — inflammation is a desirable natural response to injury and illness. Instead, when the immune response has served its purpose, SPMs down-regulate the process to resolve the inflammation.

Produced in the tissues around the affected area, SPMs function as “resolution agonists” targeting the immune cells that mediate the inflammatory response. By binding to specific cellular receptors, particularly the types known as “G-protein coupled receptors,” SPMs modify cell behavior to promote resolution.

The SPMs mediators — lipoxins, resolvins, protectins, and maresins — are derived from arachidonic acid and omega-3 fatty acids.

Arachidonic acid is often seen as an undesirable pro-inflammatory metabolite of omega-6 fatty acid. But as in many other aspects of the immune system, push and pull both have their place.

SPMs in effect signal the immune system to stop actively responding and instead to accelerate the return to homeostasis.

SPMs play a unique role in helping the body finally shut down the immune response, inhibit additional inflammation, clear away the damaging byproducts of the inflammatory process, and aid tissue remodeling.

SPMs can facilitate the resolution even of prolonged or chronic inflammation. And once the SPMs have done their job, the body naturally breaks them down and eliminates them.

For more information about Dr. Silverman, please visit www.drrobertsilverman.com or Facebook.com/drrobertsilverman.
 

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Helping a patient resolve a chronic inflammatory condition is one of the biggest challenges a holistic practitioner faces.
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