Dr. Robert G. Silverman is a chiropractic doctor, clinical nutritionist and author of, “Inside-Out Health: A Revolutionary Approach to Your Body,” an Amazon No. 1 bestseller in 2016. The ACA Sports Council named Dr. Silverman “Sports Chiropractor of the Year” in 2015. He also maintains a busy private practice as founder of Westchester Integrative Health Center, which specializes in the treatment of joint pain using functional nutrition along with cutting-edge, science-based, nonsurgical approaches.

Dr. Silverman is also on the advisory board for the Functional Medicine University and is a seasoned health and wellness expert on both the speaking circuits and within the media. He has appeared on FOX News Channel, FOX, NBC, CBS, CW affiliates as well as The Wall Street Journal and NewsMax, to name a few. He was invited as a guest speaker on “Talks at Google” to discuss his current book. As a frequent published author in peer-reviewed journals and other mainstream publications, including Integrative Practitioner, MindBodyGreen, Muscle and Fitness, The Original Internist and Holistic Primary Care journals, Dr. Silverman is a thought leader in his field and practice.

Tags: gut bacteria | dopamine | dementia | brain

Gut Bacteria and Brain Health

Thursday, 01 August 2019 04:13 PM Current | Bio | Archive

Recent research confirms the idea that gut health and brain health are tightly linked. Metabolites excreted by gut bacteria are sensed by afferent nerve endings in the gut; their level is reported to the brain via the vagus nerve.

Bacterial metabolites include some substances that are very similar to brain neurotransmitters such as dopamine. In other words, microbial metabolites can interact with the brain and influence behavior and feelings.

The human gut contains more than a thousand species of bacteria. Trillions of individual bacteria are in the gut, meaning the human body contains more bacteria just in the gut than cells in the entire body.

The gut microbiome weighs about three pounds. It contains 20 million bacteria genes; the human body has only about two thousand.

And the gut contains far more neurotransmitter chemicals than the brain itself. In fact, about 90 percent of the body’s serotonin is produced in the gut by enterochromaffin (EC) cells.

The process is highly dependent on the presence of gut bacteria. The bacteria grow and produce metabolites within the gut that stimulate the EC cells to produce serotonin.

Gut bacteria metabolites may also be important in a number of neurodegenerative diseases. In autism, for example, gut microbiota appear to alter the immune system and metabolism.

People with autism often have higher intestinal permeability and show a higher antigenic load from gut bacteria. Their gut biome bacteria are less diverse, and Candida is twice as abundant.

People with autism also have higher than usual levels of LPS (lipopolysaccharides, also known as endotoxin) in their blood. LPS is released from the outer cell walls of gram-negative bacteria when they are destroyed. LPS leads to inflammation that carries over from the digestive tract to the bloodstream.

The presence of antibodies against LPS in the blood indicates that the endotoxin has infiltrated the systemic circulation through the intestinal wall — well-known leaky gut syndrome. LPS elicits a strong immune response that may be closely related to autism symptoms.

Similarly, elevated LPS from intestinal permeability is noted in brain disorders such as Alzheimer’s disease, cognitive decline, dementia, and mood disorders.

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Recent research confirms the idea that gut health and brain health are tightly linked.
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Thursday, 01 August 2019 04:13 PM
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