Dr. Mehmet Oz is host of the popular TV show “The Dr. Oz Show.” He is a professor in the Department of Surgery at Columbia University and directs the Cardiovascular Institute and Complementary Medicine Program and New York-Presbyterian Hospital.

Dr. Mike Roizen is chief medical officer at the Cleveland Clinic Wellness Institute, an award-winning author, and has been the doctor to eight Nobel Prize winners and more than 100 Fortune 500 CEOs.


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Tags: hypercortisolemia | biotin | thyroid | Dr. Oz

Biotin Can Skew Test Results

By and Wednesday, 13 June 2018 04:24 PM Current | Bio | Archive

In the 1994 Jim Carrey film "The Mask," timid bank clerk Stanley Ipkiss discovers a magical mask that transforms him into a manic, confident (and green) playboy with supernatural powers.

As the movie showed, masking can cause a lot of trouble.

A few months ago we told you about a medical masking: The Food and Drug Administration warned that too much biotin (vitamin B-7) can mask test results for a clinical biomarker (troponin) that helps docs diagnose a heart attack.

High doses of biotin can skew test results for thyroid hormones, which can lead to an overdiagnosis of Graves' disease or hyperthyroidism.

But biotin can cause even more masking trouble. A case report in the Journal of the Endocrine Society reveals that someone taking 5,000 micrograms of biotin daily (a common dosage sold over the counter, even though 30 micrograms is adequate for good skin, nail, and liver health) seemed to test positive for hypercortisolemia, believed to be caused by a testosterone-producing tumor.

That, the report says, "led to weeks of psychological distress ... nearly resulting in an unnecessary invasive procedure."

Now, moms-to-be and breastfeeding moms may need to take B-7 (ask your doc; the dose in a prenatal multivitamin usually suffices) to assure proper fetal development and infant health.

But the rest of you: If you have two to three daily servings of 100 percent whole grains; eat walnuts, pecans and almonds; get half a multivitamin twice a day; and have at least a couple servings of wild salmon and trout each week, you don't need biotin supplements.

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High doses of biotin can skew test results for thyroid hormones, which can lead to an overdiagnosis of Graves' disease or hyperthyroidism.
hypercortisolemia, biotin, thyroid, Dr. Oz
Wednesday, 13 June 2018 04:24 PM
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