Dr. Chauncey W. Crandall, author of Dr. Crandall’s Heart Health Report newsletter, is chief of the Cardiac Transplant Program at the world-renowned Palm Beach Cardiovascular Clinic in Palm Beach Gardens, Fla. He practices interventional, vascular, and transplant cardiology. Dr. Crandall received his post-graduate training at Yale University School of Medicine, where he also completed three years of research in the Cardiovascular Surgery Division. Dr. Crandall regularly lectures nationally and internationally on preventive cardiology, cardiology healthcare of the elderly, healing, interventional cardiology, and heart transplants. Known as the “Christian physician,” Dr. Crandall has been heralded for his values and message of hope to all his heart patients.

Tags: psoriasis | heart risk | inflammatory skin condition | cardiovascular disease risk

Psoriasis and Heart Risk

Wednesday, 03 Oct 2012 08:40 AM


Millions of Americans suffer from psoriasis, a common inflammatory skin condition that puts them at increased risk for cardiovascular disease. But exactly why this occurs wasn’t known, until now.

Using genetically engineered mice, researchers have been able to demonstrate that the same autoimmune disease that causes inflamed patches on the skin also causes inflammation of the heart.

First, researchers at Case Western Reserve University of Medicine were able to use genetic engineering to develop a skin condition in mice that is similar to human psoriasis. Then they teamed up with the colleagues in the university’s cardiovascular department and compared these mice with normal mice, to see if they developed cardiac complications that mimicked those seen in human psoriasis patients.

They found that the mice with the psoriasis-type condition had blood that was more likely to clot than the normal mice, and that the walls of the coronary arteries in the genetically engineered mice also became inflamed. These findings are similar to what happens to adult humans with coronary heart disease.

But perhaps most important to patients with psoriasis, the researchers were also able to demonstrate that reversing the psoriasis decreased the risk of heart disease.


© HealthDay

   
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Millions of Americans suffer from psoriasis, a common inflammatory skin condition that puts them at an increased risk for cardiovascular disease.
psoriasis,heart risk,inflammatory skin condition,cardiovascular disease risk
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2012-40-03
Wednesday, 03 Oct 2012 08:40 AM
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