Dr. Russell Blaylock, author of The Blaylock Wellness Report newsletter, is a nationally recognized board-certified neurosurgeon, health practitioner, author, and lecturer. He attended the Louisiana State University School of Medicine and completed his internship and neurological residency at the Medical University of South Carolina. For 26 years, practiced neurosurgery in addition to having a nutritional practice. He recently retired from his neurosurgical duties to devote his full attention to nutritional research. Dr. Blaylock has authored four books, Excitotoxins: The Taste That Kills, Health and Nutrition Secrets That Can Save Your Life, Natural Strategies for Cancer Patients, and his most recent work, Cellular and Molecular Biology of Autism Spectrum Disorders. Find out what others are saying about Dr. Blaylock by clicking here.
Tags: glutamate | neurotransmitter | immunity | vaccines

Glutamate Kills Brain Cells

Tuesday, 16 Jan 2018 03:52 PM Current | Bio | Archive

In my book Excitotoxins: The Taste that Kills, I reviewed the scientific literature linking the body and brain’s immune reactions to a growing number of neurological conditions.

Since that book was published, research in this field has virtually exploded, and neuroscientists now realize that excitotoxicity is one of the most important processes in nearly all brain disorders.

Excitotoxicity occurs when brain cells are exposed to an amino acid called glutamate. When this happens, the cells become “excited,” and within little over an hour they die.

That is, they are excited to death — hence excitotoxicity.

Glutamate is one of many types of neurotransmitters in the nervous system. These special chemicals allow brain cells to communicate with each other.

You may have heard of other neurotransmitters, such as serotonin, dopamine, and acetylcholine. New research has shown that glutamate receptors are found on every brain cell, and that glutamate helps regulate the other neurotransmitters.

In addition, it is now known that the brain contains very specialized receptors for glutamate, and that glutamate is the most abundant neurotransmitter in the brain, accounting for 90 percent of all cortical neurotransmission.

Because glutamate can kill brain cells, even in relatively low concentrations, the brain expends a lot of energy to keep the levels low outside of the cell.

Inside brain cells, however, glutamate is relatively harmless. In healthy brain cells the concentration of glutamate outside is one thousand times lower than inside.

Every time the brain is inflamed, excitotoxicity is triggered, and it can become chronic. In addition, many things that stimulate the body’s immune system can also rapidly activate the brain’s immune system.

For example, if you catch a virus, you may start to feel fatigued, have difficulty thinking clearly, and become irritable.

This happens because the body’s immune reaction to the virus has also activated the brain’s immune system (even though the virus is not in the brain), causing what is called “sickness behavior.” Vaccines can have the same effect.

As we begin to age, our microglia start activating by themselves, and become much more sensitive to activation by the body’s immune system.

Studies have shown that older people feel the effects of a viral infection much longer than young people, and are more likely to suffer permanent damage to the brain.

In addition, as we age our brain becomes progressively more inflamed. This explains why the risk of developing a neurodegenerative disease becomes much higher as we age.

Another factor that is less well-appreciated is that older people also have higher brain glutamate levels — and it is this factor that is doing most of the damage.

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New research has shown that glutamate receptors are found on every brain cell, and that glutamate helps regulate the other neurotransmitters.
glutamate, neurotransmitter, immunity, vaccines
Tuesday, 16 Jan 2018 03:52 PM
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