In both animal models and human cases of epilepsy, there are high levels of glutamate and low levels of taurine in the hippocampus, which means that the brain is hyperexcitable.
In animal models of epilepsy, taurine has been shown to reduce seizures.
In the few studies done on humans with seizures, taurine initially reduced the incidence of seizures but over a long period the seizures returned.
There are several reasons why this may have happened. One is that taurine is slow to enter the brain and may require higher doses taken over a longer period.
In addition, many foods contain excitotoxin additives in high concentrations, which would counteract the benefits of the taurine.
Early studies suggested that in people with epilepsy, supplementing with taurine not only raised taurine levels in the spinal fluid but also lowered the high levels of glutamate. High levels of glutamate are associated with causing the seizures.
Because high levels of free radicals and lipid peroxidation products and inflammation are all associated with seizures, things that reduce these processes, such as taurine, curcumin, luteolin, apigenin, resveratrol, hesperidin, DHA oils, magnesium, and quercetin would all reduce the risk of seizures occurring — especially if used in combination.
It is also important to avoid sugar and high glycemic foods, because hypoglycemia is a major trigger for seizures. A high intake of vegetables, avoiding red meats, and avoiding omega-6 oils will also reduce seizures.
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