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Dr. Russell Blaylock, M.D.
Dr. Russell Blaylock, author of The Blaylock Wellness Report newsletter, is a nationally recognized board-certified neurosurgeon, health practitioner, author, and lecturer. He attended the Louisiana State University School of Medicine and completed his internship and neurological residency at the Medical University of South Carolina. For 26 years, practiced neurosurgery in addition to having a nutritional practice. He recently retired from his neurosurgical duties to devote his full attention to nutritional research. Dr. Blaylock has authored four books, Excitotoxins: The Taste That Kills, Health and Nutrition Secrets That Can Save Your Life, Natural Strategies for Cancer Patients, and his most recent work, Cellular and Molecular Biology of Autism Spectrum Disorders. Find out what others are saying about Dr. Blaylock by clicking here.
Tags: cancer | glutamate | glutamine | metabolism

Forgotten Factors in Cancer Control

Russell Blaylock, M.D. By Tuesday, 21 September 2021 04:39 PM EDT Current | Bio | Archive

Cancer cells have abnormal metabolism. Mainly, this is because they use a process called aerobic glycolysis for energy. (Normal cells use a different process called the electron transport system.)

Glucose is the main fuel for cancers, and therefore all carbohydrates feed cancers. But cancer cells have other fuels. It turns out that they can use the amino acid glutamine just as efficiently as they use glucose.

In fact, some tumors are voracious glutamine consumers. Within cancer cells, glutamine is converted into another amino acid called glutamate, which is used for energy production and to stimulate receptors on the cancer cell membrane, triggering increased proliferation of cancer cells and invasion into surrounding tissues.

The list of cancers that have been shown to have glutamate receptors include:

• Colon cancer

• Breast cancer

• Prostate cancer

• Thyroid cancer

• Lymphoma

• Leukemia

• Lung cancer

• Bone cancers

• Pancreatic cancer

• Nasopharyngeal cancer

• Brain cancer

Some cancers, such as melanomas and medulloblastomas, have very high numbers of glutamate receptors. Blocking glutamate receptors has been shown to inhibit the growth and invasion of these tumors and greatly enhance the effectiveness of conventional treatments.

Most diets, even those advocated by cancer center dietitians, contain high levels of glutamate, glutamine, and sugar.

Unfortunately, cancer patients are rarely told that they should avoid foods naturally high in glutamate and glutamine, and processed foods containing powerful glutamate additives, such as MSG, whey protein, hydrolyzed protein, soy protein, caseinate, natural flavors, carrageenan, and autolyzed yeast.

Foods naturally high in glutamate include all meats, fish, many cheeses, green peas, all soy products, beans, tomatoes (especially pureed or as a sauce), and many salad dressings, as well as milk and milk products.

While a ketogenic diet has powerful anticancer effects, high glutamate foods should be excluded from that diet. Inside cells, glutamine is converted into glutamate by the enzyme glutaminase. Research has shown that inhibiting this enzyme slows cancer growth.

The highest concentration of glutamine in the body is found in muscles. Terminal cancer patients lose a great deal of muscle and become emaciated (cancer cachexia) because the tumors steal the glutamine from their muscles in massive amounts.

The answer to this problem seems to be blocking the glutaminase enzyme, as that prevents the cells from manufacturing glutamate. But you also have to eliminate glutamate from the diet.

© 2023 NewsmaxHealth. All rights reserved.

Glucose is the main fuel for cancers, and therefore all carbohydrates feed cancers. But cancer cells have other fuels.
cancer, glutamate, glutamine, metabolism
Tuesday, 21 September 2021 04:39 PM
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