Newsmax TV & Webwww.newsmax.comFREE - In Google Play
Newsmax TV & Webwww.newsmax.comFREE - On the App Store
Tags: science | gene | dna | fatty live | weight loss

Scientists Find a Way to Disable Obesity Gene

an overweight woman walks away from the camera
(Rogelio V. Solis/AP)

By    |   Wednesday, 06 May 2020 07:17 PM EDT

Seeking to solve one of the mankind's expanding health mysteries, scientists might have found a way to disable the obesity gene, according to The Science Times.

The Washington University School of Medicine in St. Louis believes it has a proof of concept with the potential to help obese people burn fat at rates of lean people.

The research led by Dr. Steven L. Teitelbaum has been able to disable a gene in mice cells that has shown to prevent mice from becoming obese even if fed a high-fat diet, per the study published in The Journal of Clinical Investigation.

"Myeloid-specific ASXL2 deletion limits diet-induced obesity by regulating energy expenditure," the study of mice found. 

The study homes in on inflammatory cells called macrophages, because obesity has been correlated with chronic low-grade inflammation. Modulating the activity of the inflammatory cells revealed obese mice burned calories at the rate of mice that were not obese, per the Times.

The research deleted the ASXL2 gene in obese mice in one experiment and, in a second, injected nanoparticles to meddle with the gene's activity. 

The study piggybacked Touro College in New York research that found obese humans and mice burn fewer calories than those who are not obese.

The treated mice burned 45% more calories than those not treated in Dr. Teitelbaum's research, per the Times.

Also, the mice did not get fatty liver disease, where fat builds in the liver and causes the fat to be stored elsewhere. Scientists have found fatty liver disease as a cause of obesity and diabetes.

A co-author of the study, Nidhi Rohatgi, believes the treatment helped get the white fat cells that store fat and lead to obesity to behave like brown fat cells, which help burn fat, per the Times.

Eric Mack

Eric Mack has been a writer and editor at Newsmax since 2016. He is a 1998 Syracuse University journalism graduate and a New York Press Association award-winning writer.

© 2024 Newsmax. All rights reserved.

Scientists might have found a way to disable the obesity gene in a study of mice, which burn calories in the same way as humans do, The Science Times reported.
science, gene, dna, fatty live, weight loss
Wednesday, 06 May 2020 07:17 PM
Newsmax Media, Inc.

Sign up for Newsmax’s Daily Newsletter

Receive breaking news and original analysis - sent right to your inbox.

(Optional for Local News)
Privacy: We never share your email address.
Join the Newsmax Community
Read and Post Comments
Please review Community Guidelines before posting a comment.
Find Your Condition
Get Newsmax Text Alerts

The information presented on this website is not intended as specific medical advice and is not a substitute for professional medical treatment or diagnosis. Read Newsmax Terms and Conditions of Service.

Newsmax, Moneynews, Newsmax Health, and Independent. American. are registered trademarks of Newsmax Media, Inc. Newsmax TV, and Newsmax World are trademarks of Newsmax Media, Inc.

© Newsmax Media, Inc.
All Rights Reserved
© Newsmax Media, Inc.
All Rights Reserved