Tags: Cancer | hpv | cancer | head | neck | oral | cervical

HPV Linked to Head and Neck Cancers

HPV Linked to Head and Neck Cancers
(Copyright DPC)

By    |   Friday, 22 January 2016 10:57 AM

A strain of human papillomavirus (HPV-16) — tied to cervical, oral and throat cancer — has been found to increase the risk for a certain type of head and neck cancers by 22 times.

Researchers at Albert Einstein College of Medicine have determined when HPV-16 is detected in peoples' mouths, they are 22 times more likely than those without HPV-16 to develop a type of head and neck cancer.

The study, published online in JAMA Oncology, is the first to show that HPV-16's presence in the mouth precedes the development of oropharyngeal cancers.

The findings, by Drs. Ilir Agalliu and Robert D. Burk, are based on an analysis of the medical records of nearly 97,000 people taking part in two large, national health studies. At the start of the studies, participants provided mouthwash samples and were cancer-free.

Over the four years of the study, 132 cases of head and neck cancer were identified among the participants.

In follow-up comparisons, the researchers found people with HPV-16 in their mouthwash samples were 22 times more likely to develop oropharyngeal cancer than a comparable group of study participants with no detectable HPV-16 in their samples.

In addition, the researchers found for the first time that the presence of other types of oral HPV were also associated with the development of head and neck cancers, indicating a broader role for HPVs in causing these cancers than has been recognized to date.

The upshot: Oral mouthwash samples may help in predicting people's risk for developing head and neck cancers.

This study was funded, in part, by the National Institutes of Health.

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Cancer
A strain of human papillomavirus - tied to cervical, oral and throat cancer - has been found to increase the risk for a certain type of head and neck cancers by 22 times.
hpv, cancer, head, neck, oral, cervical
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2016-57-22
Friday, 22 January 2016 10:57 AM
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