Tags: Cancer | breast | cancer | radiation | therapy | leukemia | risk

Leukemia Risk After Breast Radiation Higher Than Thought: Johns Hopkins

By    |   Tuesday, 23 December 2014 12:06 PM

There is a small risk of developing leukemia after treatment for early stage breast cancer but now researchers have found this increase could be twice as high as previously reported, a new study shows.
Researchers looked at 20,063 breast cancer patients treated at eight U.S. cancer centers between 1998 and 2007 and found that 50 of those patients had developed some form of leukemia within 10 years after radiation therapy, chemotherapy or a combination of the two.
The retrospective study estimated the risk at about 0.5 percent, which was double the 0.25 percent previously found.
Antonio Wolff, M.D., a professor of oncology at the Johns Hopkins University School of Medicine in Baltimore, which led the research, said this study could help early-stage breast cancer patients and their physicians think more carefully about the use of chemotherapy for “just-in-case” reasons, especially when patients have a low risk of cancer recurrence.
In recent years, research has found that postsurgical chemotherapy for breast cancer mostly benefits a small and select group of patients and it is no longer recommended for all patients with Stage 1 breast cancer.
 Each breast cancer case should be evaluated individually and factors such as tumor size, whether it has spread and its genetic makeup must be considered, Dr. Wolff noted.

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Women who undergo radiation therapy to treat breast cancer have double the risk of developing leukemia than previously thought, say researchers at the John Hopkins Kimmel Cancer Center. The scientists reviewed data on more than 20,000 breast cancer victims who had undergone...
breast, cancer, radiation, therapy, leukemia, risk
Tuesday, 23 December 2014 12:06 PM
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