Tags: Cancer | blood | test | biopsy | multi-protein | biomarkers | breast

Blood Test Reduces Breast Biopsies Up to 67 Percent

Blood Test Reduces Breast Biopsies Up to 67 Percent
(Copyright DPC)

By    |   Wednesday, 24 May 2017 11:31 AM

A blood test for breast cancer that detects multi-protein biomarkers helps diagnose breast cancer, and can help women and their doctors make better decisions after an abnormal mammogram. The "liquid biopsy" could reduce the risk of tissue biopsies by up to 67 percent.

"When a mammogram yields an abnormal result, the challenge for every clinician is to decide which patients need follow-up, further imaging or biopsy," said radiologist Josie R. Alpers. "A test that is well-validated in a prospective trial means clinicians have a new way to accurately identify which patients may or may not need additional follow-up."

A study, which was published in Clinical Breast Cancer, evaluated the Videssa® Breast test among women ages 25 to 50 with abnormal or difficult-to-interpret imaging. "We know imaging has limitations, especially among women under age 50 who, because of confounding factors, are more difficult to image," said Dr. Judith K. Wolf.

When used in combination with imaging, the blood test improved diagnostic accuracy and confidence in patients with uncertain imaging results.

Depending on a patient's age, approximately 70 to 90 percent of breast biopsies conducted after an abnormal mammogram are benign. The new technique, since it rules out the necessity for biopsy in a majority of patients, increases the percentage of tissue biopsies that yield a breast cancer diagnosis from one in 11 to one in four.

"This research shows that Videssa® Breast can be a powerful new tool in the diagnostic toolbox for clinicians," Wolf said.

"With about 1.6 million breast biopsies performed each year, the implications of a blood test that can help clinicians confidently rule out breast cancer and avoid a potentially unnecessary biopsy are tremendous," she said.

According to breastcancer.org, about 12 percent of women will develop invasive breast cancer during their lifetime. About 252,710 new cases of invasive breast cancer will be diagnosed in 2017 along with about 63,410 additional cases of in situ breast cancer. About 40,610 American women will die from the disease this year.

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A blood test for breast cancer that detects multi-protein biomarkers helps diagnose breast cancer, and can help women and their doctors make better decisions after an abnormal mammogram. The "liquid biopsy" could reduce the risk of tissue biopsies by up to 67 percent."When...
blood, test, biopsy, multi-protein, biomarkers, breast, cancer
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2017-31-24
Wednesday, 24 May 2017 11:31 AM
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