Tags: Cancer | blood | cancer | drug | captisol | multiple | myeloma

Blood Cancer Drug Shows Effectiveness

Wednesday, 23 April 2014 08:26 AM

Spectrum Pharmaceuticals Inc said its experimental blood cancer drug was shown to be safe and effective in a mid-stage trial, sending its shares up 10 percent.

The injectable drug, Captisol-enabled melphalan, an improved form of common chemotherapy drug melphalan, is being tested in patients with multiple myeloma undergoing stem cell transplants.
 
High-dose chemotherapy in combination with stem cell transplants is an option for patients with multiple myeloma, a form of blood cancer that originates in the bone marrow.

The higher dose of chemotherapy given during the treatment destroys more myeloma cells. But it also kills normal blood-producing stem cells in the bone marrow, which must be replaced in order to restore blood cell production.

The drug is free of propylene glycol found in available melphalan products that has been associated with renal and cardiac side-effects.

The biotechnology company said it expects to file for U.S. marketing approval in the third quarter.

Spectrum Pharmaceuticals acquired development and marketing rights to the drug from Ligand Pharmaceuticals Inc in March 2013.

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Spectrum Pharmaceuticals Inc said its experimental blood cancer drug was shown to be safe and effective in a mid-stage trial, sending its shares up 10 percent.The injectable drug,Captisol-enabled melphalan, an improved form of common chemotherapy drug melphalan, is being...
blood, cancer, drug, captisol, multiple, myeloma
176
2014-26-23
Wednesday, 23 April 2014 08:26 AM
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